The YC Startup Fixing Healthcare’s $260B Problem
- S2E70
- 40:36
- November 18th 2025
Hospitals are bleeding $260 billion a year to denied insurance claims — and AI is making it worse. One YC founder decided to fight back, using AI to beat insurers at their own game.
In this episode, we dive deep into how Aegis, a Y Combinator startup, is using AI agents to help healthcare providers recover billions lost to claim denials. Founder Ong shares his journey from Calcutta to Carnegie Mellon to YC, the inside story of getting into YC at the last minute, and how his team is tackling one of healthcare’s most entrenched problems.
What you’ll learn:
- How YC companies are attacking trillion-dollar industries with AI
- Why healthcare loses $260B a year to denied insurance claims
- The hidden incentives driving insurers to deny payments
- How Aegis built real traction in just 10 weeks
- What YC really teaches founders beyond the playbook
- The power of the YC network and why it still compounds after demo day
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Chapters:
00:00 The YC Application Journey
00:48 Introducing Krishang from Aegis
01:21 Krishang's Entrepreneurial Background
02:30 The Birth of Aegis
04:53 The Power of YC Content
07:03 Getting into YC: The Application Process
10:00 The YC Batch Experience
14:25 Maintaining Momentum Post-YC
17:59 Advice for Aspiring YC Applicants
19:09 Tackling the Healthcare Industry
21:41 Targeting Medical Billing Companies
22:07 AI in Insurance: A Growing Challenge
22:21 The Impact on Hospitals
24:31 Investor Perspectives on AI in Healthcare
26:48 Strategies for Success in Healthcare Startups
33:12 The YC Advantage
33:49 The Power of the YC Network
38:14 Silicon Valley's Collaborative Ecosystem
39:58 Conclusion and Final Thoughts
🎧 Listen on the go:
Spotify: https://open.spotify.com/show/1u1JyRKH8JYFjhBkvTUOAP
Apple: https://apple.co/4cZ8RMm
My other YouTube Channel: https://www.youtube.com/@GJarrosson
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